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Productname |
 CH50 Eq MicroVue™ Quidel® |
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Total classical complement pathway activity
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Cat-No. |
A018 |
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Range |
Appr. 0 - 300 U Eq/ml |
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Incubation time |
3.5 hours |
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Sample volume |
14 µl (dilute 1:200) |
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Sample type |
Serum ONLY. Plasma CANNOT be used.
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Sample preparation |
The proper collection, storage and shipment of specimens are essential, since complement may be activated in improperly handled specimens. Assay immediately or keep on ice for testing within 4 hours, up to 3 days at 4°C. For long-term storage, freeze at -70 ºC. Maximum 6 freeze/thaw cycles.
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Reference values |
133 ± 54 U Eq/ml
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Species |
Human, cynomolgus macaque
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Specificity |
The monoclonal antibody specific to terminal complement complexes arising as the result of the activation step in the test.
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Tests |
96 Tests |
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Method |
ELISA |
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Product informations |
- Literature: Complement Diagnostics (pdf-File 1,850 kb)
- Kit Instructions (pdf-File 205 kb)
- Cross-reaction all species (pdf-File 71 kb)
- Information: Monitoring Complement Activation SC5b-9, C5a &CH50 (pdf-File 100 kb)
- Information (pdf-File 679 kb) |
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Intended use |
The binding of C1q component of C1 to immune complexes triggers the classical complement pathway. This activation results in a cascade of enzymatic and non-enzymatic reactions, culminating in the formation of terminal complement complexes (TCC). Under standard conditions, the level of TCC that can be generated in serum is a quantitative expression of the serum’s total classical complement activity. The MicroVue CH50 Eq EIA is designed to measure the total classical complement pathway activity in human serum samples. The measurement of CH50 allows detection of deficiencies of one or more complement components
(C1 through C9).
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Keywords product |
CH50 Eq, ELISA, (C1-C9) Complement component deficiency, Total classical complement pathway activity, Biocompatibility, Hemocompatibility, Complement pathway, Complement cascade
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