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Product name |
iC3b MicroVue™ Quidel® |
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Quantification of the iC3b fragment of C3 Protein
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Cat-No. |
A006 |
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Range |
0.2 - 2.0 µg/ml |
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Incubation time |
1.5 hours |
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Sample volume |
100 µl (after dilution 1:25 – 1:200) |
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Sample type |
Serum and EDTA-plasma
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Sample preparation |
The proper collection and storage of specimens is essential, since C3 is highly susceptible to proteolysis and hydrolysis. Serum or EDTA plasma specimens should be collected aseptically using standard techniques. They should be tested immediately or stored at 4 ºC or on ice until assayed. This should not exceed 4 hours. For long-term storage, freeze at -70 ºC within 2 hours after collection.
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Species |
Human
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Specificity |
Anti-iC3b monoclonal anti body specifically binds iC3B and not to C3.
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Tests |
96 Tests |
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Method |
ELISA |
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Product informations |
- Literature: Complement Diagnostics (pdf-File 1,850 kb)
- Kit Instructions (pdf-File 185 kb)
- Cross-reaction all species (pdf-File 71 kb)
- Datasheet (pdf-File 510 kb) |
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Intended use |
The iC3b enzyme immunoassay measures the amount of the iC3b fragment in human plasma or serum, as well as in other biological fluids, experimental samples or mixtures.
The levels of iC3b can be significantly elevated in the serum and plasma of some patients with complex-associated diseases such as rheumatoid arthritis and systemic lupus erythmatosus. iC3b levels may also be elevated in body fluids from other patients with infections, burns, myocardial infarctions, glomerulonephritis, and acute respiratory distress syndrome.
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Keywords product |
iC3b, ELISA, Rheumatoid Arthritis, Immune complex-associated disease, iC3b-Fragment, Complement pathway, Complement cascade
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